Overview and Discovery of IgNARs and Generation of VNARs
关键词: overview discovery ignars generation来源: 互联网
Immunoglobulin new antigen receptors (IgNARs) from sharks are a distinct class of immune receptors, consisting of homodimers with no associated light chains. Antigen binding is encapsulated within single VNAR immunoglobulin domains of 13–14 kDa in size. This small size and single domain format means that they exhibit considerable stability and are readily produced in heterologous protein expression systems. In this chapter, I describe the history and discovery of IgNARs, the development of VNAR biotechnology, and highlight important factors in VNAR protein production.
推荐方法
- 人补体片段C5a(C5a)ELISA试剂盒 说明书
- 直接凝集反应技术(Direct agglutination reaction technique)
- 关于ELISPOT的问题
- 免疫组化双染实验流程
- 抗体的标记方法
- Screening for Complement Deficiency
- Purification and Analysis of Strep-tagged Antibody-Fragments
- Methods to Identify and Characterize Inhibitors of Bacterial RNA Polymerase
- Fluorogenic Substrates as Detectors of Caspase Activity During Natural Killer Cell-Induced Apoptosis
- Detection of SLE Antigens in Neutrophil Extracellular Traps (NETs)