手性分析；中药与天然药物质量控制；有机小分子及体内药物分析；多肽及反义核酸药物研究与评价

Chiral Recognition in Separation Methods: Mechanisms and Applications

上一篇 / 下一篇 2010-06-20 14:36:18/ 个人分类：分析技术

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Chiral Recognition in Separation Methods: Mechanisms and Applications

By Alain Berthod

•Publisher:   Springer
•Number Of Pages:   337
•Publication Date:   2010-08-29
•ISBN-10 / ASIN:   3642124445
•ISBN-13 / EAN:   9783642124440

Product Description:

The importance of chiral interactions for both preparative and analytical separations, particularly for pharmaceutical applications, is underlined by numerous publications in this field. Here, for the first time, a team of experienced analysts from industry and academe presents a comprehensive review of the various mechanisms that result in enantiomer separations. A better understanding of these processes is crucial for setting as well as improving chiral separation procedures and also for developing new applications. The coverage in this book includes a range of separation methods, such as gas, liquid, or countercurrent chromatography, and capillary electrophoresis. The special case of chiral ionic liquids is examined in detail. Most modern chiral selectors are discussed, including derivatized polysaccharide- and cyclodextrin-based selectors, along with a newly introduced class of carbohydrates: the cyclofructose selectors. This publication will be required reading not only for research and development departments in the pharmaceutical and cosmetic industries, but also for researchers in toxicology, environmental monitoring, and food research.

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