A Birds Eye View of the Bacterial Landscape
Bacteria interact with the environment through their cell surface. Activities as diverse as attaching to a catheter, crawling on a surface, swimming through a pond, or being preyed on by a bacteriophage depend on the composition and structure of the cell surface. The cell surface must also protect bacteria from harmful chemicals present in the environment while allowing the intake of nutrients and excretion of toxic molecules. Bacteria have evolved four main types of bacterial cell surfaces to accomplish these functions: those of the typical gram-negative and gram-positive bacteria, and those of the Actinobacteria and Mollicutes . So few types seems remarkable since bacteria are very diverse and abundant, and they can live in many different environments. However, each species has tweaked these stereotypical bacterial surfaces to best fit its needs. The result is an amazing diversity of the bacterial landscape, most of which remains unexplored. Here I give an overview of the main features of the bacterial cell surface and highlight how advances in methodology have moved forward this field of study.
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