热门搜索词：
Genetic Distance and Markers Used in Linkage Mapping
In this chapter, we focus on maps and markers used for a linkage analysis. More detail regarding the actual linkage analysis methodology follows in Chapter 11. There are two major types of maps: genetic maps and physical maps. Genetic maps indicate the expected number of meiotic crossover events between two loci on a chromosome and are measured in centiMorgans (cM). Physical maps use molecular techniques, such as DNA sequencing, to determine the location of markers on a chromosome and are measured in base pairs (bp). Linkage analysis relies on genetic maps, and hence they are discussed in this chapter. In addition to a discussion of genetic maps and various map functions, we also discuss the selection of markers for a linkage analysis, including the more traditional microsatellite markers and the newer single nucleotide polymorphism (SNP) markers.
- Inhibition of Gene Expression In Vivo Using Multiplex siRNA
- Design of a Herpes Simplex Virus Type 2 Long Oligonucleotide-Based Microarray: Global Analysis of HSV-2 Transcript Abundance Dur
- Sex Determination by PCR Analysis of the X-Y Amelogenin Gene
- Comparative Genomic Hybridization: Microarray Design and Data Interpretation
- Chromosome Preparation from Hematological Malignancies
- Genome-Wide Platelet RNA Profiling in Clinical Samples
- Use of Aptamer Tagging to Identify In Vivo Protein Binding Partners of Small Regulatory RNAs
- Preparation of Long Templates for RNA In Vitro Transcription by Recursive PCR
- Introduction to Genome Biology: Features, Processes, and Structures
- Production of Multicopy shRNA Lentiviral Vectors for Antiviral Therapy
移动版：