The severity of injury and degree of recovery following experimental spinal cord injury (SCI) utilizing several electrophysiological tests (SSEP, MEP, H-reflex) are described in other chapters. This chapter summarizes tests of spinal cord physiology, including spinal cord blood flow, spinal cord field potential mapping, EMG, and PO2 monitoring of the spinal cord. Physiological assessment of the spinal cord provides objective evaluation of nonelectrophysiological importance that is of value in assessing responses to novel therapies following experimental SCI.