Rodent Models of Experimental Autoimmune Uveitis
The model of experimental autoimmune uveitis (EAU) in mice and in rats is described. EAU targets immunologically privileged retinal antigens and serves as a model of autoimmune uveitis in humans as well as a model for autoimmunity in a more general sense. EAU is a well-characterized, robust, and reproducible model that is easily followed and quantitated. It is inducible with synthetic peptides derived from retinal autoantigens in commonly available strains of rats and mice. The ability to induce EAU in various gene-manipulated, including HLA-transgenic, mouse strains makes the EAU model suitable for the study of basic mechanisms as well as in clinically relevant interventions.
- 制作胶体金试纸的硝酸纤维素膜选择及应用技巧
- SOCS蛋白以负反馈环路调控细胞因子的信号转导
- 表现遗传学中DNA的修饰――DNA甲基化
- 免疫组化中五花八门的问题解决
- 酶标抗体结合物的纯化
- macrophage dichloromethylene diphosphonate)
- Investigating Human T Cell Lymphotropic Retrovirus (HTLV) Tax Function with Molecular and Immunophenotypic Techniques
- Induction of Tolerogenic Dendritic Cells by NF-B Blockade and Fc Receptor Modulation
- Immunotube Selections
- ELISA Inhibition Assay