CD71分子
CD71 分子 CD71 常用单克隆抗体或代号: OKT9;(TfR) 主要表达细胞: Mac,增殖细胞 [NL] 分子质量(kDa)和结构: p95(同源二聚体) 功 能:结合白细胞生长 CD71 Aka transferrin receptor Present on actively proliferating cells; essential for iron transport into proliferating cells (benign and malignant) Ferrotransferrin binds CD71 at neutral pH, is internalized to an acidic endosomal compartment Iron-free apotransferrin remains bound to CD71 at pH 5, is returned to cell surface, where pH rises to 7.4. At neutral pH, apotransferrin loses affinity for receptor, is released into circulation, allowing a new cycle to begin Positive staining (normal): all proliferating cells plus iron requiring cells: reticulocytes, erythroid precursors, capillary endothelium in brain Positive staining (disease): AML M6, primary effusion lymphoma
- MHCI类分子荷肽
- 帮忙分析一下抗原与弗氏不完全佐剂乳化不好的
- 猪瘟单克隆抗体ELISA
- ELISA实验原理、步骤、ELISA问题分析
- 酶标抗体制备技术条件及方法
- 免疫耐受现象的发现
- 疫苗的分类
- User-Friendly Expression Plasmids Enable the Fusion of VHHs to Application-Specific Tags
- Preparation of Broth and Plates
- Optical Methods for the Measurement and Manipulation of Cytosolic Free Calcium in Neutrophils