INTRODUCTION The objective of this study was to determine the nephrotoxic potential to male rats of selected hydrocarbon materials when administered neat by oral intubation five days per week over a four-week period. Each material was administered at 0.5 and 2.0 g/kg. The study was conducted in three phases. Phase I was initiated on June 2@ 1983 and terminated on June 29@ 1983; Phase II was initiated on July 20@ 1983 and terminated on August 16@ 1983: and Phase II I was initiated on March 21@ 1984 and terminated on April 17@ 1984. Each phase had a control group that was dosed with isotonic1c saline at a dose level of 2.0 g/kg. In addition. for each phase API PS-6- Fuel was dosed at 0.5 and 2.0 g/kg and served as a reference control.
PUBL 32-30966-1985由API - American Petroleum Institute 发布于 1985-02-01,并于 2011-03-16 实施。
* 在 PUBL 32-30966-1985 发布之后有更新,请注意新发布标准的变化。
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