DIN EN ISO 21427-2:2009
水质.通过微核诱变测量进行遗传毒性评估.第2部分:利用V79细胞系的混合种群法(ISO 21427-2:2006),英文版本DIN EN ISO 21427-2:2009-08

Water quality - Evaluation of genotoxicity by measurement of the induction of micronuclei - Part 2: Mixed population method using the cell line V79 (ISO 21427-2:2006); English version of DIN EN ISO 21427-2:2009-08

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标准号

DIN EN ISO 21427-2:2009

发布

2009年

发布单位

德国标准化学会

当前最新

DIN EN ISO 21427-2:2009

 

 

引用标准

ISO 5667-16

被代替标准

DIN EN ISO 21427-2:2008

适用范围

This part of ISO 21427 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster. The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes. The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation.

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