实验方法>
生物化学技术>
化学生物学实验技术>Chemical Mismatch Cleavage Analysis by Capillary Electrophoresis with Laser-Induced Fluorescence Detection
Chemical Mismatch Cleavage Analysis by Capillary Electrophoresis with Laser-Induced Fluorescence Detection
关键词: chemical mismatch cleavage来源: 互联网
The chemical mismatch cleavage (CMC) analysis was first described by Cotton et al. (1 ) and has successfully been used for detection and identification of mutations in several genes implicated in causing human genetic disorders (2 -7 ). Compared with some current methods, such as denaturing gradient gel electrophoresis (8 ) and singlestranded conformation polymorphism (SSCP) which detects polymorphism in short DNA fragments, CMC has a higher diagnostic sensitivity and can analyze larger DNA fragment lengths (9 ).
推荐方法
- Chemokine Receptor Interactions with Virus-Like Particles
- 人纤溶酶原激活物抑制因子 (PAI)酶联免疫分析
- 茭白
- Chromatin Endogenous Cleavage and Psoralen Crosslinking Assays to Analyze rRNA Gene Chromatin In Vivo
- Assays for RING Family Ubiquitin Ligases
- 氨基酸纸层析法原理和操作步骤
- 杂环化合物
- 生物技术成为人类新救星
- A Simple Solid-Phase Competition Assay with Labeled Antigen
- 定磷法测定核酸的含量