PUBL 29-33104-1982

ACUTE TOXICITY TESTS PARAFFINIC OIL SAMPLE 78-9 NOMINAL VISCOSITY 70 SUS/100 DEGREES F

PUBL 29-33104-1982 发布历史

ABSTRACT The test material@ API 78-9@ Paraffinic Oil (70SUS/100??@ was tested for potential acute toxicity using a battery of six tests: Primary Dermal Irritation@ Primary Eye Irritation@ Acute Dermal Toxicity@ Acute Oral Toxicity@ Skin Sensitization@ and Subacute Dermal Toxicity. Materials@ methods@ and results of individual tests are presented in this report. The test material produced no eye irritation and only minimal primary skin irritation effects. Neither systemic toxicity nor mortality were produced in the acute dermal or acute oral studies; a dermal LD50 and an oral LD50 greater than 5 g/kg were established. Based on histopathologic observations on the subacute dermal toxicity study@ API 78-9 produced slight dermal irritation and inflammation upon repeated dermal exposure over 21 days. Results of the skin sensitization study revealed the test material to be non-sensitizing.

PUBL 29-33104-1982由API - American Petroleum Institute 发布于 1982-06-01，并于 2009-03-13 实施。

PUBL 29-33104-1982的历代版本如下：

• 1982年06月01日 PUBL 29-33104-1982

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标准号

PUBL 29-33104-1982

发布日期

1982年06月01日

实施日期

2009年03月13日

废止日期

无

中国标准分类号

/

国际标准分类号

/

发布单位

API - American Petroleum Institute

引用标准

71

适用范围

ABSTRACT The test material@ API 78-9@ Paraffinic Oil (70SUS/100??@ was tested for potential acute toxicity using a battery of six tests: Primary Dermal Irritation@ Primary Eye Irritation@ Acute Dermal Toxicity@ Acute Oral Toxicity@ Skin Sensitization@ and Subacute Dermal Toxicity. Materials@ methods@ and results of individual tests are presented in this report. The test material produced no eye irritation and only minimal primary skin irritation effects. Neither systemic toxicity nor mortality were produced in the acute dermal or acute oral studies; a dermal LD50 and an oral LD50 greater than 5 g/kg were established. Based on histopathologic observations on the subacute dermal toxicity study@ API 78-9 produced slight dermal irritation and inflammation upon repeated dermal exposure over 21 days. Results of the skin sensitization study revealed the test material to be non-sensitizing.