CD59分子
关键词: CD59 单克隆抗体 抑制来源: 互联网
CD59 分子 CD59 常用单克隆抗体或代号: MEM- 43,YTH53.1;(TAP,Protectin) 主要表达细胞: 广泛 [NL] 分子质量(kDa)和结构: gp18- 20(GPI连接) 功 能: 与CD2结合,结合C8、C9,抑制MAC CD59 Aka protectin Regulates complement mediated cell lysis by inhibiting formation of membrane attack complex (MAC) Genetic defects that cause a reduction or loss of both CD59 and CD55 on erythrocytes produce paroxysmal nocturnal hemoglobinuria (PNH) Incorporated into HIV envelope, protects virus and HIV infected cells against complement deposition Expression on erythrocytes important for their survival Positive staining (normal): most cells
推荐方法
- ELISA检测筛选到的靶分子结合肽
- 补体调节蛋白
- 固有免疫应答中的免疫细胞
- 免疫荧光技术(immunofluorescence)
- APAAP免疫组化实验操作过程
- Real-Time PCR Methods to Study Expression of Genes Related to Hypermutability
- Purification of C1q Receptors and Functional Analysis
- Photolabeling the Transporter Associated with Antigen Processing
- Measurement of Complement Hemolytic Activity, Generation of Complement-Depleted Sera, and Production of Hemolytic Intermediates
- High-Level Production of a Humanized ImmunoRNase Fusion Protein from Stably Transfected Myeloma Cells