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高通量测序技术在肠道菌群多样性研究中的应用（三）

2020.7.06

一、饮食、能量摄取、肥胖与肠道菌群之间的关系：

1. A core gut microbiome in obese and lean twins——2009《Nature》——if 36.10

2. An obesity-associated gut microbiome with increased capacity for energy harvest

——2006《Nature》——if 36.10

3. Functional metagenomics to mine the human gut microbiome for dietary fiber catabolic enzymes——2010《Genome Res》——if 13.58

4. High-fat diet determines the composition of the murine gut microbiome independently of obesity——2009《Gastroenterology》——if 12.03

5. Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models——2010《Gut》——if 10.61

6. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa——2010《PNAS》——if 9.770

7. Human gut microbiota in obesity and after gastric bypass——2009《PNAS》——if 9.770

8. Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice——2010《ISME J》——if 6.152

9. Use of pyrosequencing and DNA barcodes to monitor variations in Firmicutes and Bacteroidetes communities in the gut microbiota of obese humans——2008《BMC Genomics》——if 4.205

10. Responses of gut microbiota to diet composition and weight loss in lean and obese mice——2011《Obesity》——if 3.530

11. The effect of diet on the human gut microbiome: A metagenomic analysis in humanized gnotobiotic mice——2009《Sci Transl Med》——if 3.510

12. Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans——2011《Am J Clinc Nutr》

二、肠道菌群与疾病发生之间的关联

1. Microbes and Health Sackler Colloquium: Human oral, gut, and plaque microbiota in patients with atherosclerosis——2010《PNAS》——if 9.770

2. The macaque gut microbiome in health, lentiviral infection, and chronic enterocolitis

——2008《PLoS Pathog》——if 9.079

3. Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model——2009《ISME J》——if 6.152

4. Redefining the role of intestinal microbes in the pathogenesis of necrotizing enterocolitis——2010《Pediatrics》——if 5.390

5. Towards the human colorectal cancer microbiome——2011《PLoS One》——if 4.410

6. Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults——2010《PLoS One》——if 4.410

7. Structural shifts of gut microbiota as surrogate endpoints for monitoring host health changes induced by carcinogen exposure——2010《FEMS Microbiol Ecol》——if 3.456

三、抗生素治疗对肠道菌群的影响

1. Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans——2010《J Clin Invest》——if 14.15

2. Reshaping the gut microbiome with bacterial transplantation and antibiotic intake——2010《Genome Res》——if 13.58

3. The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing——2008《PLoS Biol》——if 12.46

4. Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome——2010《PLoS One》——if 4.410

5. Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation——2009《IAI》——if 4.098

6. Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis——2010《Mucosal Immunol》——if 3.627

四、不同个体肠道微生物群落结构及其受其他外界因素（压力、致病菌感染、手术）的影响

1. Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency——2010《Gastroenterology》——if 12.03

2. Depletion of luminal iron alters the gut microbiota and prevents Crohn’s disease-like ileitis——2010《Gut》——if 10.61

3. Composition, variability, and temporal stability of the intestinal microbiota of the elderly——2011《PNAS》——if 9.770

4. Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors——2010《PNAS》——if 9.770

5. Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins——2010《PNAS》——if 9.770

6. Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla——2009《PNAS》——if 9.770

7. Comparative analysis of human gut microbiota by barcoded pyrosequencing——2008《PLoS One》——if 4.410

8. Community-wide response of gut microbiota to enteropathogenic Citrobacter rodentium infection revealed by deep sequencing——2009《IAI》——if 4.098

9. Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by Citrobacter rodentium——2010《IAI》——if 4.098

10. Intestinal microbial ecology in premature infants assessed with non-culture-based techniques——2010《J Pediatr》——if 4.041

11. Sampling and pyrosequencing methods for characterizing bacterial communities in the human gut using 16S sequence tags——2010《BMC Microbiol》——if 2.960

12. Quantitative assessment of the human gut microbiome using multitag pyrosequencing——2010《Chem Biodivers》——if 1.585

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